I notice crackling of audio when just playing audio streams. Changed every setting remotely related to hardware usage and/or virtualization, changed guest audio drivers, changed host audio/video drivers and settings throughout the OS, even did a clean install of a Windows 10 guest and the same issues occurred. I've tried every combination of troubleshooting in the book to resolve the issue. Seemingly all started after the Anniversary Update - like most others have mentioned. I've been dealing with the same issue with a Windows 10 host and Windows 10 Guest for quite some time now.
Finally signed up for an account to add my two cents in as well.
